Dr Josu de la Fuente is a highly experienced and trained consultant paediatric haematologist who specialises in non-malignant haematolocy, including haemoglobinopathies and bone marrow failures in Harley Street, London, and advises on all blood problems in infancy, children and young people. He is a leading specialist in bone marrow transplantation directing a programme at St. Mary's Hospital, London. He is also known for developing a unique and innovative clinical and research programme for Diamond Blackfan anaemia at Imperial College Healthcare and is on the Specialist Haematology Register.
Dr de la Fuente graduated with a
degree in Medicine and Surgery from the University of the Basque Country in
Spain in 1994. He completed his general training in paediatrics in a number of
hospitals in London and later undertook further training in haematology at
Imperial College and Great Ormond Street Hospital. Throughout his haematology
training, he developed an interest in red cell disorders, bone marrow failure
and transplantation. He became an MRC Clinical Research Fellow, gaining his PhD
after undertaking research into human developmental haemopoiesis.
Experienced paediatric haematologist in Harley Street
He is currently the Clinical Lead for
Paediatric Specialities at Imperial College Healthcare NHS Trust, an Honorary
Senior Lecturer at Imperial College London, in addition to the Clinical Lead in
Haematology and Director of the Blood and Marrow Transplant Programme at St
Mary’s Hospital. Dr De La Fuente is also a member and haematology lead in the
Paediatric Medicine Clinical Reference Group of NHS England and member of the
iBFM Study Group steering committee for chronic myeloid leukaemia.
Paediatric conditions and treatments offered by Dr de la
With Dr de la Fuente’s significant expertise and skill, he
is able to offer high quality treatment for a range of paediatric
haematological conditions including:
Anaemias due to
Sickle cell disease
Bone marrow failure,
including Diamond Blackfan anameia, Fanconi anaemia and dyskeratosis congenita
including immune thrombocytopenia and immune neutropenia
Blood disorders of
newborn and infancy
Clotting problems and
The Paediatric Bone and Marrow Transplant Programme at St
Mary’s Hospital, Imperial College Healthcare
As the director of the Paediatric Bone and Marrow Transplant
Programme, Dr de la Fuente majorly contributed to the development of unique
protocols for the transplantation of haemoglobinopathies (sickle cell disease and thalassaemia) and bone marrow failure syndromes and led the use of alternative
donors for patients who do not have a suitable family donor.
The Paediatric BMT Programme based at the Department of Paediatrics at Imperial College Healthcare is one of the leading bone marrow transplant units and centre of excellence in the UK for adolescents and children with non-malignant blood disorders comprising haemoglobinopathies, inherited bone marrow failure and aplastic anaemia.
Dr de la Fuente has developed a unique clinical and research programme for Diamond Blackfan anaemia constituting the largest clinical programme in a single institution worldwide and making significant advances in the characterisation and understanding of the disease.
Dedicated and caring paediatric haematologist
Dr de la Fuente understands that suffering from a blood disorder has a very significant impact on children and their families and that undertaking treatment or a bone marrow transplant, if required, is difficult for any family, which is why he takes the time to
prepare families for their treatment by giving plenty of time and information, enabling you to make an informed decision. He works with a dedicated multidisciplinary team and your care will include access to a paediatric haematology clinical nurse specialist.
In the event that your child requires a bone marrow transplant, St Mary’s Hospital’s
dedicated team of consultants, nurses, psychologists, play specialists and
dieticians spend a year working with you to ensure that the whole family is
fully prepared for your child’s transplant intervention.
Dr de la Fuente’s work has been published several times in
many of the top peer-reviewed journals. He has also contributed to book
chapters, given numerous oral presentations and posters at scientific meetings
- Josu de la Fuente, André Baruchel, Andrea Biondi, Eveline de
Bont, Marie-Françoise Dresse, Meinolf Suttorp and Frederic Millot on behalf of
the International BFM Group (iBFM) Study Group Chronic Myeloid Leukaemia
Committee. How I manage CML in Children. Guidelines for the management of chronic
myeloid leukaemia in children and young people up to the age of 18 years. Accepted
for publication. British Journal of Haematology 2014.
- Tommaso Vannocci, Hitoshi Kurata, Josu de la Fuente, Irene
A. Roberts and Andrew C. G. Porter. Nuclease-stimulated homologous
recombination at the human β-globin gene. J Gene Med Februar7 2014.
- Irene AG Roberts and Josu de la Fuente. Stem cell transplantation for thalassemia and
sickle cell disease. Chapter 17. Hematopoietic Stem Cell Transplantation in
Clinical Practice. 1st Edition. Elsevier.2008. Editors: Jennifer G. Treleaven
and A. John Barrett.
- Irene Roberts and Josu de la Fuente. Haemopoietic Stem Cell
Transplantation for Haemoglobinopathies. ESH-EBMT Handbook on Haematopoietic
Stem Cell Transplantation 5th Edition (2008). Editors: J. Apperley, E.
Carreras, E. Gluckman, A. Gratwohl, T. Masszi.
Oral presentations at scientific meetings
- Deena Iskander, Yvonne Harrington, Gareth Gerrard, Alex en
Foong, Letizia Foroni, Irene Roberts, Anastasios Karadimitris and Josu de la
Fuente. Patients with Diamond Blackfan Anaemia have Abnormalities of Cellular
and Humoral Immunity. Diamond Blackfan Anaemia International Consensus
Conference Atlanta 2014.
- Lucia Gargiulo, Michela Sica, Maria Papaioannou, Giulia Talini,
Aristeidis Chaidos, Barbara Richichi, Andrei V Nikolaev, Cristina Nativi, Mark
Layton, Josu de la Fuente, Irene Roberts, Lucio Luzzatto, Rosario Notaro, and
Anastasios Karadimitris. Autoreactive T Cells From Patients with Paroxysmal
Nocturnal Hemoglobinuria (PNH) Specifically Recognize Glycosyl-
Phosphatidyl-Inositol (GPI). Blood (ASH Annual Meeting Abstracts), Nov 2012;
Posters at scientific meetings
- Gareth Gerrard, Hui-En Foong, Deena Iskander, Mikel
Valganon, Dalia Kasperaviciute, Michael Muller, Yvonne Harrington, Irene
Roberts, Anastasios Karadimitris, Letizia Foroni and Josu de la Fuente. The
application of high-throughput targeted genomics for the molecular
characterisation of Diamond-Blackfan anaemia: a cohort study. Diamond Blackfan
Anaemia International Consensus Conference Atlanta 2014.
- Josu de la Fuente, Farah O'Boyle, Yvonne Harrington, Nancy
O'Brien, Natalie Killeen, Subarna Chakravorty, Leena Karnik, Richard Szydlo and
Irene Roberts. Fludarabine/Treosulfan/Thiotepa/ATG Conditioning Leads To High
Rates Of Long-Term Engraftment and Low Toxicity Enabling The Use Of Mismatched
and Unrelated Donors For Transplantation In Haemoglobinopathies. Blood 2013